ELECTROPHILIC AMINATION - 1ST DIRECT TRANSFER OF NHBOC WITH LI TERT-BUTYL-N-TOSYLOXYCARBAMATE

被引：54

作者：

GENET, JP

MALLART, S

GRECK, C

PIVETEAU, E

机构：

[1] Lab. de Synthese Organique associe au C.N.R.S. Ecole Nationale Superieure de Chimie de Paris -, 75231 Paris cedex 03, 11, rue P. et M. Curie

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 21期

关键词：

D O I：

10.1016/S0040-4039(00)79923-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Lithium t-butyl-N-tosyloxycarbamate (LiBTOC) has been found to be an electrophilic aminating reagent. This species reacts with organometallic reagents, ester enolates and alpha-cuprophosphonates to provide primary amines as well as alpha-aminocarboxylic and phosphonic esters in their N-(Boc) protected form. (35-80 % isolated yields).

引用

页码：2359 / 2362

页数：4

共 27 条

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