NONQUATERNARY CHOLINESTERASE REACTIVATORS .4. DIALKYLAMINOALKYL THIOESTERS OF ALPHA-KETO THIOHYDROXIMIC ACIDS AS REACTIVATORS OF ETHYL METHYLPHOSPHONYL AND 1,2,2-TRIMETHYLPROPYL METHYLPHOSPHONYL-ACETYLCHOLINESTERASE INVITRO

被引：17

作者：

BEDFORD, CD ^{[1
]}

MIURA, M ^{[1
]}

BOTTARO, JC ^{[1
]}

HOWD, RA ^{[1
]}

NOLEN, HW ^{[1
]}

机构：

[1] SRI INT,BIOMED RES LAB,MENLO PK,CA 94025

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 09期

关键词：

D O I：

10.1021/jm00159a021

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1689 / 1696

页数：8

共 32 条

[1]

Albert A., 1962, IONIZATION CONSTANTS

[2]

BAKER EL, 1978, LANCET, V1, P31

[3] STRUCTURE ACTIVITY RELATIONSHIPS FOR REACTIVATORS OF ORGANOPHOSPHORUS-INHIBITED ACETYLCHOLINESTERASE - QUATERNARY-SALTS OF 2-[(HYDROXYIMINO)METHYL]IMIDAZOLE [J].

BEDFORD, CD ;

HARRIS, RN ;

HOWD, RA ;

MILLER, A ;

NOLEN, HW ;

KENLEY, RA .

JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (11) :1431-1438

[4]

BRACHWITZ H, 1966, Z CHEM, V6, P313

[5] EFFECT OF 1-(AR)ALKYL-2-HYDROXYIMINOMETHYL-PYRIDINIUM SALTS ON REACTIVATION AND AGING OF ACETYLCHOLINESTERASE INHIBITED BY ETHYL DIMETHYLPHOSPHORAMIDOCYANIDATE (TABUN) [J].

DEJONG, LPA ;

WOLRING, GZ .

BIOCHEMICAL PHARMACOLOGY, 1978, 27 (18) :2229-2235

[6] REACTIVATION AND AGING OF CYCLOPENTYL METHYLPHOSPHONYLATED ACETYLCHOLINESTERASE IN THE PRESENCE OF SOME 1-ALKYL-2-HYDROXYIMINOMETHYL-PYRIDINIUM SALTS [J].

DEJONG, LPA ;

WOLRING, GZ .

BIOCHEMICAL PHARMACOLOGY, 1978, 27 (24) :2911-2917

[7] OXIMES ANTAGONISTIC TO INHIBITORS OF CHOLINESTERASE .1. [J].

ELLIN, RI ;

WILLS, JH .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1964, 53 (09) :995-&

[8]

ENGLEHARD N, 1957, ANGEW CHEM INT ED EN, V6, P615

[9] ACYL DERIVATIVES OF HYDROXYLAMINE .13. CONFIGURATION AND CONFORMATION OF HYDROXAMIC ACID DERIVATIVES CONTAINING SULFUR [J].

EXNER, O ;

BENN, MH ;

WILLIS, F .

CANADIAN JOURNAL OF CHEMISTRY, 1968, 46 (11) :1873-&

[10] NEW SUBSTITUENT CONSTANT PI DERIVED FROM PARTITION COEFFICIENTS [J].

FUJITA, T ;

HANSCH, C ;

IWASA, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (23) :5175-&

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