AN INITIAL EVALUATION OF NABILONE IN THE CONTROL OF RADIOTHERAPY-INDUCED NAUSEA AND VOMITING

被引:31
作者
PRIESTMAN, TJ
PRIESTMAN, SG
机构
关键词
D O I
10.1016/S0009-9260(84)80088-4
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
A pilot study was undertaken to assess the efficacy of Nabilone in controlling radiotherapy-induced vomiting resistant to a conventional anti-emetic (metoclopramide). Cancer patients (30) receiving wide-field upper abdominal irradiation were prospectively monitored. Fourteen developed no significant nausea or vomiting and in 10 symptoms were controlled by metaclopramide. All 6 patients who failed to respond to this agent responded to Nabilone. Toxicity with both drugs was minimal. Although patient numbers were small, this initial assessment suggests that Nabilone may be a useful agent in the control of resistant radiation-induced sickness.
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页码:265 / 266
页数:2
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