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AN INITIAL EVALUATION OF NABILONE IN THE CONTROL OF RADIOTHERAPY-INDUCED NAUSEA AND VOMITING
被引:31
作者:
PRIESTMAN, TJ
PRIESTMAN, SG
机构:
关键词:
D O I:
10.1016/S0009-9260(84)80088-4
中图分类号:
R8 [特种医学];
R445 [影像诊断学];
学科分类号:
1002 ;
100207 ;
1009 ;
摘要:
A pilot study was undertaken to assess the efficacy of Nabilone in controlling radiotherapy-induced vomiting resistant to a conventional anti-emetic (metoclopramide). Cancer patients (30) receiving wide-field upper abdominal irradiation were prospectively monitored. Fourteen developed no significant nausea or vomiting and in 10 symptoms were controlled by metaclopramide. All 6 patients who failed to respond to this agent responded to Nabilone. Toxicity with both drugs was minimal. Although patient numbers were small, this initial assessment suggests that Nabilone may be a useful agent in the control of resistant radiation-induced sickness.
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页码:265 / 266
页数:2
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