RETENTION CHARACTERISTICS OF AN ALUMINUM-OXIDE HPLC COLUMN

被引：10

作者：

CSERHATI, T

机构：

[1] Central Research Institute for Chemistry, Hungarian Academy of Sciences, Budapest, H-1525

来源：

CHROMATOGRAPHIA | 1990年 / 29卷 / 11-12期

关键词：

Alumina adsorbent; Column liquid chromatography; Retention data; Substituted anilines;

D O I：

10.1007/BF02261229

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The retention of 29 aniline derivatives was determined by high performance liquid adsorption chromatography using an alumina column and dichloromethane-n-hexane mobile phases in various vol. ratios. The retention parameters of anilines (log k′ and the slope and intercept value of the correlation between log k′ and the dichloromethane concentration in the eluent) were correlated with the physicochemical parameters (lipophilicity and adsorption capacity of silica) of aniline derivatives. The retention of anilines decreased with their increasing lipophilicity and increased with their increasing silica adsorption capacity. The alumina columns was found to be an appropriate support for the adsorptive phase separation of polar compounds as aniline derivatives. © 1990 Friedr. Vieweg & Sohn Verlagsgesellschaft mbH.

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页码：593 / 596

页数：4

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