IDENTIFICATION OF AN OCTAMER-BINDING SITE IN THE HUMAN KAPPA-LIGHT-CHAIN ENHANCER

被引：19

作者：

NELMS, K ^{[1
]}

VANNESS, B ^{[1
]}

机构：

[1] UNIV MINNESOTA,DEPT BIOCHEM,MINNEAPOLIS,MN 55455

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1990年 / 10卷 / 07期

关键词：

D O I：

10.1128/MCB.10.7.3843

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Octamer motifs contribute to the function and tissue specificity of immunoglobulin heavy- and light-chain gene promoters and the heavy-chain enhancer. A variant octamer-binding site within a conserved region of the human kappa light-chain gene enhancer which contributes to the function of this enhancer has been identified.

引用

页码：3843 / 3846

页数：4

共 29 条

[1] TANDEM KAPPA IMMUNOGLOBULIN PROMOTERS ARE EQUALLY ACTIVE IN THE PRESENCE OF THE KAPPA-ENHANCER - IMPLICATIONS FOR MODELS OF ENHANCER FUNCTION
ATCHISON, ML
PERRY, RP
[J]. CELL, 1986, 46 (02) : 253 - 262
[2] THE ROLE OF THE KAPPA-ENHANCER AND ITS BINDING-FACTOR NF-KAPPA-B IN THE DEVELOPMENTAL REGULATION OF KAPPA-GENE TRANSCRIPTION
ATCHISON, ML
PERRY, RP
[J]. CELL, 1987, 48 (01) : 121 - 128
[3] MECHANISMS THAT REGULATE IMMUNOGLOBULIN GENE-EXPRESSION
CALAME, KL
[J]. ANNUAL REVIEW OF IMMUNOLOGY, 1985, 3 : 159 - 195
[4] IDENTIFICATION OF AN OCTAMER-BINDING SITE IN THE MOUSE KAPPA LIGHT-CHAIN IMMUNOGLOBULIN ENHANCER
CURRIE, RA
ROEDER, RG
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1989, 9 (10) : 4239 - 4247
[5] THE CONSERVED DECANUCLEOTIDE FROM THE IMMUNOGLOBULIN HEAVY-CHAIN PROMOTER INDUCES A VERY HIGH TRANSCRIPTIONAL ACTIVITY IN B-CELLS WHEN INTRODUCED INTO AN HETEROLOGOUS PROMOTER
DREYFUS, M
DOYEN, N
ROUGEON, F
[J]. EMBO JOURNAL, 1987, 6 (06) : 1685 - 1690
[6] B-LINEAGE SPECIFIC INTERACTIONS OF AN IMMUNOGLOBULIN ENHANCER WITH CELLULAR FACTORS INVIVO
EPHRUSSI, A
CHURCH, GM
TONEGAWA, S
GILBERT, W
[J]. SCIENCE, 1985, 227 (4683) : 134 - 140
[7] FOSTER J, 1985, NATURE, V315, P4123
[8] SYNERGISM BETWEEN IMMUNOGLOBULIN ENHANCERS AND PROMOTERS
GARCIA, JV
BICHTHUY, LT
STAFFORD, J
QUEEN, C
[J]. NATURE, 1986, 322 (6077) : 383 - 385
[9] CELL TYPE-SPECIFICITY ELEMENTS OF THE IMMUNOGLOBULIN HEAVY-CHAIN GENE ENHANCER
GERSTER, T
MATTHIAS, P
THALI, M
JIRICNY, J
SCHAFFNER, W
[J]. EMBO JOURNAL, 1987, 6 (05) : 1323 - 1330
[10] IDENTIFICATION AND PARTIAL-PURIFICATION OF A PROTEIN-BINDING TO THE HUMAN-IMMUNOGLOBULIN KAPPA-ENHANCER KAPPA-E2 SITE
GIMBLE, JM
FLANAGAN, JR
RECKER, D
MAX, EE
[J]. NUCLEIC ACIDS RESEARCH, 1988, 16 (11) : 4967 - 4988

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