CHARACTERISTICS OF HEMOLYTIC AND HEMAGGLUTINATING ACTIVITIES OF TREPONEMA-DENTICOLA

被引：50

作者：

GRENIER, D

机构：

[1] Departement de Sante Buccale, Université de Montreal, Montreal, Quebec

来源：

ORAL MICROBIOLOGY AND IMMUNOLOGY | 1991年 / 6卷 / 04期

关键词：

HEMOLYSIS; HEMAGGLUTINATION; TREPONEMA-DENTICOLA;

D O I：

10.1111/j.1399-302X.1991.tb00485.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Treponema denticola, a suspected periodontal pathogen, was shown to agglutinate and lyse human red blood cells. Both activities were cell-associated, heat-labile, and produced during the exponential growth phase. Hemolytic activity was time-dependent and required incubation at 37-degrees-C; further incubation at 4-degrees-C increased the hemolysis. Hemagglutination was reduced in the presence of D-glucosamine, EDTA or sodium salicylate, whereas hemolytic activity was affected by calcium chloride, magnesium chloride, EDTA or sodium salicylate. These biological activities may favor a higher concentration of hemin-containing compounds in periodontal sites, and therefore represent additional potential virulence mechanisms.

引用

页码：246 / 249

页数：4

共 23 条

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