SYSTEMIC LUPUS-ERYTHEMATOSUS INDUCED BY OVULATION INDUCTION TREATMENT

被引：58

作者：

BENCHETRIT, A

BENCHETRIT, E

机构：

[1] HADASSAH UNIV HOSP,DIV MED,RHEUMATOL UNIT,IL-91120 JERUSALEM,ISRAEL

[2] SHAARE ZEDEK MED CTR,JERUSALEM,ISRAEL

来源：

ARTHRITIS AND RHEUMATISM | 1994年 / 37卷 / 11期

关键词：

D O I：

10.1002/art.1780371109

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Infertile women are treated with various regimens for ovulation induction. The ultimate end-result of these treatments is a significant rise in levels of serum gonadotropins and estradiol-the most potent natural estrogen. Estrogens may affect diverse biologic functions, including immune and inflammatory reactions. A role for estrogens in the development or exacerbation of systemic lupus erythematosus (SLE) has been suggested by many studies. In this report, we present 3 cases of otherwise healthy women who received ovulation induction agents and subsequently developed full-blown SLE. The possible association between this treatment and SLE is discussed.

引用

页码：1614 / 1617

页数：4

共 15 条

[1] SUBSET-SPECIFIC EFFECTS OF SEX-HORMONES AND PITUITARY GONADOTROPINS ON HUMAN LYMPHOCYTE-PROLIFERATION INVITRO [J].