IMMUNOPATHOGENESIS AND IMMUNOTHERAPY OF PSORIASIS

被引:28
作者
GRIFFITHS, TW [1 ]
GRIFFITHS, CEM [1 ]
VOORHEES, JJ [1 ]
机构
[1] UNIV MICHIGAN,MED CTR,DEPT DERMATOL,TAUBMAN CTR 1910,ANN ARBOR,MI 48109
关键词
D O I
10.1016/S0733-8635(18)30038-X
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Overwhelming evidence exists to support the importance of T lymphocytes and other immunologically competent cells in the pathogenesis of psoriasis. We have used a cell-by-cell approach to examine the immunopathogenic roles of both epidermal and dermal components. The immunopharmacologic targeting of these various cellular and molecular events has provided new treatments and fresh insights into this disease.
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页码:739 / &
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