BIOCHEMICAL-PROPERTIES AND PURIFICATION OF METALLO-BETA-LACTAMASE FROM BACTEROIDES-FRAGILIS

被引：43

作者：

BANDOH, K

MUTO, Y

WATANABE, K

KATOH, N

UENO, K

机构：

[1] Inst. of Anaerobic Bacteriol., Gifu University, School of Medicine

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1991年 / 35卷 / 02期

关键词：

D O I：

10.1128/AAC.35.2.371

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The beta-lactamase from Bacteroides fragilis GAI-30144 hydrolyzed imipenem, oxyiminocephalosporins, cephamycins, and penicillins. Enzyme activity was inhibited by EDTA. Zinc completely reversed inactivation of the enzyme by EDTA. The molecular mass of purified enzyme was estimated to be 33,000 daltons.

引用

页码：371 / 372

页数：2

共 10 条

[1] BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3
[2] BETA-LACTAMASE-MEDIATED IMIPENEM RESISTANCE IN BACTEROIDES-FRAGILIS
CUCHURAL, GJ
MALAMY, MH
TALLY, FP
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1986, 30 (05) : 645 - 648
[3] PATHOGENIC ANAEROBES
FINEGOLD, SM
[J]. ARCHIVES OF INTERNAL MEDICINE, 1982, 142 (11) : 1988 - 1992
[4] BIOCHEMICAL-PROPERTIES OF BETA-LACTAMASE PRODUCED BY LEGIONELLA-GORMANII
FUJII, T
SATO, K
MIYATA, K
INOUE, M
MITSUHASHI, S
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1986, 29 (05) : 925 - 926
[5] MACROLIDE ACCUMULATION BY BACTEROIDES-FRAGILIS ATCC-25285
MUTO, Y
BANDOH, K
WATANABE, K
KATOH, N
UENO, K
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1989, 33 (02) : 242 - 244
[6] NEU HC, 1986, ANTIBIOTICS LABORATO, P757
[7] PURIFICATION AND PROPERTIES OF INDUCIBLE PENICILLIN BETA-LACTAMASE ISOLATED FROM PSEUDOMONAS-MALTOPHILIA
SAINO, Y
KOBAYASHI, F
INOUE, M
MITSUHASHI, S
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1982, 22 (04) : 564 - 570
[8] BIOCHEMICAL-PROPERTIES OF BETA-LACTAMASE PRODUCED BY FLAVOBACTERIUM-ODORATUM
SATO, K
FUJII, T
OKAMOTO, R
INOUE, M
MITSUHASHI, S
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1985, 27 (04) : 612 - 614
[9] SEQUENCING THE GENE FOR AN IMIPENEM-CEFOXITIN-HYDROLYZING ENZYME (CFIA) FROM BACTEROIDES-FRAGILIS TAL2480 REVEALS STRONG SIMILARITY BETWEEN CFIA AND BACILLUS-CEREUS BETA-LACTAMASE .2.
THOMPSON, JS
MALAMY, MH
[J]. JOURNAL OF BACTERIOLOGY, 1990, 172 (05) : 2584 - 2593
[10] PROPERTIES OF NOVEL BETA-LACTAMASE PRODUCED BY BACTEROIDES-FRAGILIS
YOTSUJI, A
MINAMI, S
INOUE, M
MITSUHASHI, S
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1983, 24 (06) : 925 - 929

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