NASOGASTRIC AND INTRAVENOUS INFUSIONS OF (+)-4-PROPYL-9-HYDROXYNAPHTHOXAZINE (PHNO) IN PARKINSONS-DISEASE

被引：14

作者：

COLEMAN, RJ

QUINN, NP

TRAUB, M

MARSDEN, CD

机构：

[1] INST NEUROL,LONDON WC1N 3BG,ENGLAND

[2] MERCK SHARP & DOHME LTD,HARLOW,ESSEX,ENGLAND

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1990年 / 53卷 / 02期

关键词：

D O I：

10.1136/jnnp.53.2.102

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

(+)-4-propyl-9-hydroxynaphthoxazine (PHNO) is a new dopamine agonist which is capable of producing a sustained response in parkinsonian patients with 'on-off' fluctuations when given as a continuous infusion either nasogastrically or intravenously. These data suggest that a sustained release formulation of PHNO may provide a significant, new treatment for patients with 'on-off' fluctuations.

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页码：102 / 105

页数：4

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