HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD FOR THE DETERMINATION OF MANGIFERIN, LIKVIRITIN AND DIHYDROQUERCETIN IN RAT PLASMA AND URINE

被引：30

作者：

GEODAKYAN, SV ^{[1
]}

VOSKOBOINIKOVA, IV ^{[1
]}

KOLESNIK, JA ^{[1
]}

TJUKAVKINA, NA ^{[1
]}

LITVINENKO, VI ^{[1
]}

GLYZIN, VI ^{[1
]}

机构：

[1] MOSCOW MED ACAD,FAC PHARMACEUT SCI,DEPT ORGAN CHEM,5TH PARKOVAJA ST 21,MOSCOW 105043,USSR

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1992年 / 577卷 / 02期

关键词：

D O I：

10.1016/0378-4347(92)80262-O

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The use of reversed-phase high-performance liquid chromatography for the determination of the biologically active plant phenolic compounds mangiferin, likviritin and dihydroquercetin is described. Perchloric acid (35%) was used for deproteinization in the case of mangiferin and likviritin, and acidified methanol for dihydroquercetin. Detection was performed at 254, 275 and 290 nm for mangiferin, likviritin and dihydroquercetin in plasma, and 365, 312 and 290 nm in urine, respectively. The limit of detection was 0.2-mu-g/ml for plasma and 0.5-mu-g/ml for urine.

引用

页码：371 / 375

页数：5

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