POLYMERIC GASTROINTESTINAL MR CONTRAST AGENTS

被引:8
作者
TILCOCK, C
UNGER, EC
AHKONG, QF
FRITZ, T
KOENIG, SH
BROWN, RD
机构
[1] Department of Radiology, University of British Columbia, Vancouver, British Columbia, V6T 2B5
[2] Department of Radiology, University of Arizona, Tucson
[3] Ibm T. J. Watson Research Center, Yorktown Heights, New York
来源
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1991年 / 1卷 / 04期
关键词
CONTRAST ENHANCEMENT; CONTRAST MEDIA; EXPERIMENTAL STUDIES; GADOLINIUM; GASTROINTESTINAL TRACT; MR STUDIES; IRON; RELAXOMETRY;
D O I
10.1002/jmri.1880010411
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Combining either paramagnetic (gadolinium chelates) or superparamagnetic (ferrite) contrast agents with polymers such as polyethylene glycol or cellulose, or with simple sugars such as dextrose, results in mixtures that exhibit improved T1 and/or T2 relaxivity compared with that of the contrast agent alone. It is suggested that the addition of such inexpensive and nontoxic polymers or saccharides may improve the effectiveness and decrease the cost of enteric contrast agents.
引用
收藏
页码:463 / 467
页数:5
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