EPR INVESTIGATION OF THE OXOVANADIUM(LV) COMPLEXES FORMED BY THE TRIPEPTIDE GLUTATHIONE AND SOME RELATED LIGANDS IN AQUEOUS-SOLUTION

被引：41

作者：

DESSI, A

MICERA, G

SANNA, D

机构：

[1] UNIV SASSARI,DIPARTIMENTO CHIM,I-07100 SASSARI,ITALY

[2] CNR,IST APPLICAZ TECN CHIM AVANZATE PROBLEMI AGRO,I-07100 SASSARI,ITALY

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 1993年 / 52卷 / 04期

关键词：

D O I：

10.1016/0162-0134(93)80031-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Complex formation between oxovanadium(IV) and glutathione (gamma-L-glutamyl-L-cysteinylglycine, GSH) was investigated in aqueous solution by EPR and electron absorption spectroscopy to identify the complexed species that were reported to form upon reduction of exogenous vanadium(V) in cellular systems. The complexing behavior of the related ligands glycine, N-acetyl-glycine, 3-mercaptopropionic acid, cysteamine, L-cysteine, N-acetyl-L-cysteine, N-acetyl-cysteamine, and oxidized glutathione (GSSG) was also examined in order to have suitable reference models. The results are compared with those reported previously.

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页码：275 / 286

页数：12

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