HIGH EFFICACY OF SHORT-TERM QUININE-ANTIBIOTIC COMBINATIONS FOR TREATING ADULT MALARIA PATIENTS IN AN AREA IN WHICH MALARIA IS HYPERENDEMIC

被引：28

作者：

METZGER, W

MORDMULLER, B

GRANINGER, W

BIENZLE, U

KREMSNER, PG

机构：

[1] INST TROPENMED,D-10179 BERLIN,GERMANY

[2] ALBERT SCHWEITZER HOSP,INT RES LAB,LAMBARENE,GABON

[3] UNIV VIENNA,DEPT INFECT DIS,A-1090 VIENNA,AUSTRIA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1995年 / 39卷 / 01期

关键词：

D O I：

10.1128/AAC.39.1.245

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In a randomized trial, a three-dose quinine monotherapy was compared with short-term combination regimens of quinine-clindamycin and quinine-doxycycline for treating adult Gabonese patients with Plasmodium falciparum malaria. In quinine-treated patients, only 38% were ultimately cured. In contrast, more than 90% of patients were cured after treatment with either combination regimen.

引用

页码：245 / 246

页数：2

共 13 条

[1]

Alecrim W D, 1982, Rev Inst Med Trop Sao Paulo, V24, P40

[2]

Barata L C, 1986, Rev Soc Bras Med Trop, V19, P135

[3]

BJORKMAN A, 1991, B WORLD HEALTH ORGAN, V69, P459

[4] SHORT-TERM ORAL CINCHONA ALKALOIDS REGIMENS FOR TREATMENT OF FALCIPARUM-MALARIA IN MADAGASCAR [J].