AMITRIPTYLINE METABOLISM - ASSOCIATION WITH DEBRISOQUIN HYDROXYLATION IN NONSMOKERS

被引：97

作者：

MELLSTROM, B ^{[1
]}

SAWE, J ^{[1
]}

BERTILSSON, L ^{[1
]}

SJOQVIST, F ^{[1
]}

机构：

[1] HUDDINGE HOSP,KAROLINSKA INST,DEPT CLIN PHARMACOL,S-14186 HUDDINGE,SWEDEN

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 1986年 / 39卷 / 04期

关键词：

D O I：

10.1038/clpt.1986.56

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：369 / 371

页数：3

共 19 条

[1] RELATIONSHIP OF N-DEMETHYLATION OF AMIFLAMINE AND ITS METABOLITE TO DEBRISOQUINE HYDROXYLATION POLYMORPHISM [J].

ALVAN, G ;

GRIND, M ;

GRAFFNER, C ;

SJOQVIST, F .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1984, 36 (04) :515-519

[2] ROLE OF OXIDATION POLYMORPHISM ON BLOOD AND URINE CONCENTRATIONS OF AMITRIPTYLINE AND ITS METABOLITES IN MAN [J].

BALANTGORGIA, AE ;

SCHULZ, P ;

DAYER, P ;

BALANT, L ;

KUBLI, A ;

GERTSCH, C ;

GARRONE, G .

ARCHIV FUR PSYCHIATRIE UND NERVENKRANKHEITEN, 1982, 232 (03) :215-222

[3] EXTREMELY RAPID HYDROXYLATION OF DEBRISOQUINE - A CASE-REPORT WITH IMPLICATION FOR TREATMENT WITH NORTRIPTYLINE AND OTHER TRICYCLIC ANTIDEPRESSANTS [J].

BERTILSSON, L ;

ABERGWISTEDT, A ;

GUSTAFSSON, LL ;

NORDIN, C .

THERAPEUTIC DRUG MONITORING, 1985, 7 (04) :478-480

[4]

BORGA O, 1972, PHARMACOLOGY FUTURE, V3, P56

[5] THEOPHYLLINE METABOLISM IN RELATION TO ANTIPYRINE, DEBRISOQUINE, AND SPARTEINE METABOLISM [J].

DAHLQVIST, R ;

BERTILSSON, L ;

BIRKETT, DJ ;

EICHELBAUM, M ;

SAWE, J ;

SJOQVIST, F .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1984, 35 (06) :815-821

[6]

EDELBROEK PM, 1984, LANCET, V1, P1123

[7] ANTIPYRINE METABOLISM IN RELATION TO POLYMORPHIC OXIDATIONS OF SPARTEINE AND DEBRISOQUINE [J].

EICHELBAUM, M ;

BERTILSSON, L ;

SAWE, J .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1983, 15 (03) :317-321

[8] CIGARETTE-SMOKING AND THEOPHYLLINE CLEARANCE AND METABOLISM [J].

GRYGIEL, JJ ;

BIRKETT, DJ .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 30 (04) :491-496

[9] DETERMINATION OF DEBRISOQUINE AND ITS 4-HYDROXY METABOLITE IN BIOLOGICAL-FLUIDS BY GAS-CHROMATOGRAPHY WITH FLAME-IONIZATION AND NITROGEN-SELECTIVE DETECTION [J].

LENNARD, MS ;

SILAS, JH ;

SMITH, AJ ;

TUCKER, GT .

JOURNAL OF CHROMATOGRAPHY, 1977, 133 (01) :161-166

[10] POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN [J].

MAHGOUB, A ;

IDLE, JR ;

DRING, LG ;

LANCASTER, R ;

SMITH, RL .

LANCET, 1977, 2 (8038) :584-586

← 1 2 →