T-CELL SUBSET RELATIONSHIPS IN THYMOCYTE DEVELOPMENT

被引：45

作者：

SCOLLAY, R

机构：

[1] Institute of Medical Research, Melbourne, Vic., The Walter and Eliza Hall

来源：

CURRENT OPINION IN IMMUNOLOGY | 1991年 / 3卷 / 02期

关键词：

D O I：

10.1016/0952-7915(91)90051-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

During the past couple of years there has been significant progress in our understanding of the development of different lineages of T cells within the thymus. Pathways, subpopulations and cellular dynamics are all becoming clearer. Signal transduction through primary and accessory receptors is also beginning to be understood. However, the exact nature of the events that lead uncommitted cells to choose a particular lineage (either alpha-beta/gamma-delta or CD4+/CD8+) has still not been determined.

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页码：204 / 209

页数：6

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