EFFECTS OF POLAR ADDITIVES ON THE ENZYME ENANTIOSELECTIVITY OF AN ESTERIFICATION REACTION IN ORGANIC-SOLVENTS

被引：6

作者：

DUAN, G

CHEN, JY

机构：

[1] Institute of Chemical Metallurgy, Academia Sinica, Beijing

来源：

BIOTECHNOLOGY LETTERS | 1994年 / 16卷 / 10期

关键词：

D O I：

10.1007/BF01022404

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The enantioselectivity of candida cylindracea lipase in esterification between ibuprofen and 1-butanol in organic solvents is influenced by adding a small amount of polar solvents. The results show that both the solvents and the amount added affected the reaction. Addition of 0.05 % ( v/v) N,N-dimethylformamide increase the ee value of the ester from 57.5 % of no addition to that of 91 %

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页码：1065 / 1068

页数：4

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