ALKALOIDS FROM THE ANTARCTIC SPONGE KIRKPATRICKIA-VARIALOSA .1. VARIOLIN-B, A NEW ANTITUMOR AND ANTIVIRAL COMPOUND

被引：162

作者：

PERRY, NB

ETTOUATI, L

LITAUDON, M

BLUNT, JW

MUNRO, MHG

PARKIN, S

HOPE, H

机构：

[1] UNIV CANTERBURY, DEPT CHEM, CHRISTCHURCH 1, NEW ZEALAND

[2] UNIV CALIF DAVIS, DEPT CHEM, DAVIS, CA 95616 USA

来源：

TETRAHEDRON | 1994年 / 50卷 / 13期

关键词：

D O I：

10.1016/S0040-4020(01)89673-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Variolin B (1), a new type of pyridopyrrolopyrimidine alkaloid with antitumour and antiviral properties, has been isolated from the Antarctic sponge Kirkpatrickia varialosa, and its structure determined by X-ray crystallography. A degradation product, variolin D (2), has been identified from its spectroscopic data.

引用

页码：3987 / 3992

页数：6

共 16 条

[1] REVERSE PHASE FLASH CHROMATOGRAPHY - A METHOD FOR THE RAPID PARTITIONING OF NATURAL PRODUCT EXTRACTS
BLUNT, JW
CALDER, VL
FENWICK, GD
LAKE, RJ
MCCOMBS, JD
MUNRO, MHG
PERRY, NB
[J]. JOURNAL OF NATURAL PRODUCTS, 1987, 50 (02): : 290 - 292
[2] HETEROCYCLIZATIONS .8. NEW POLYCYCLIC PYRIMIDINES WITH BRIDGE-HEAD NITROGEN
CAPUANO, L
SCHREPFER, HJ
MULLER, K
ROOS, H
[J]. CHEMISCHE BERICHTE-RECUEIL, 1974, 107 (03): : 929 - 936
[3] H-1 AND C-13 NMR-STUDIES OF 7-AZAINDOLE AND RELATED-COMPOUNDS
COX, RH
SANKAR, S
[J]. ORGANIC MAGNETIC RESONANCE, 1980, 14 (02): : 150 - 152
[4] BIOLOGICAL ACCOMMODATION IN BENTHIC COMMUNITY AT MCMUDO-SOUND, ANTARCTICA
DAYTON, PK
ROBILLIARD, GA
PAINE, RT
DAYTON, LB
[J]. ECOLOGICAL MONOGRAPHS, 1974, 44 (01) : 105 - 128
[5] H-H AND C-H COUPLING CONSTANTS IN NEUTRAL AND PROTONATED AZINES
GIL, VMS
PINTO, AJL
[J]. MOLECULAR PHYSICS, 1970, 19 (04) : 573 - &
[6] ALKALOIDS OF THE ANNONACEAE .33. ANNOMONTINE AND METHOXYANNOMONTINE, 2 NEW PYRIMIDINE-BETA-CARBOLINE-TYPE ALKALOIDS FROM ANNONA-MONTANA
LEBOEUF, M
CAVE, A
FORGACS, P
PROVOST, J
CHIARONI, A
RICHE, C
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1982, (05): : 1205 - 1208
[7] INVESTIGATION OF THE RELATIONSHIP BETWEEN INVERTEBRATE PREDATION AND BIOCHEMICAL-COMPOSITION, ENERGY CONTENT, SPICULE ARMAMENT AND TOXICITY OF BENTHIC SPONGES AT MCMURDO-SOUND, ANTARCTICA
MCCLINTOCK, JB
[J]. MARINE BIOLOGY, 1987, 94 (03) : 479 - 487
[8] METABOLITES OF THE ANTARCTIC SPONGE DENDRILLA-MEMBRANOSA
MOLINSKI, TF
FAULKNER, DJ
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (02) : 296 - 298
[9] AN ANTIBACTERIAL PIGMENT FROM THE SPONGE DENDRILLA-MEMBRANOSA
MOLINSKI, TF
FAULKNER, DJ
[J]. TETRAHEDRON LETTERS, 1988, 29 (18) : 2137 - 2138
[10] PIERSON V, BIOCHEM PHARMACOL, V38, P1395

← 1 2 →