TRANSPLANTATION OF KIDNEYS FROM PEDIATRIC CADAVER DONORS TO ADULT RECIPIENTS

被引:23
作者
CREAGH, TA
MCLEAN, PA
SPENCER, S
CUNNINGHAM, P
DONOVAN, MG
WALSHE, JJ
MURPHY, DM
机构
[1] Dept. of Urology/Transplant., Beaumont Hospital, Dublin
关键词
TRANSPLANTATION; TISSUE DONORS; ORGAN PROCUREMENT; KIDNEY DISEASES;
D O I
10.1016/S0022-5347(17)37972-7
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Pediatric donors (less than 12 years old) are a potentially important source of kidneys for adult recipients. Previous reports of decreased graft survival and increased complication rates have made surgeons wary of using such kidneys. In 64 kidneys from younger donors transplanted to adult recipients the delayed graft function rate (41 versus 42%), and 2 and 3-year graft survival rates (67 versus 72% and 61 versus 65%, respectively) were similar to those seen with kidneys from adult donors. Kidneys from donors 24 months old or less (5) experienced an 80% rate of graft loss at 1 year. When these kidneys are excluded the 1-year graft survival rate was similar to kidneys from older and younger donors (70 versus 77%). Mean serum creatinine at 1 year was similar in both groups (155 +/- 21 versus 151 +/- 10). Pediatric kidneys except those obtained from donors 2 years old or less are suitable for adult recipients. However, kidneys from very young donors may be more appropriate to pediatric recipients.
引用
收藏
页码:951 / 952
页数:2
相关论文
共 10 条
[1]  
BOCZKO S, 1978, GYNECOL OBSTET, V146, P387
[2]  
BROWN MW, 1988, CLIN TRANSPLANT, V2, P87
[3]   USE OF PEDIATRIC CADAVER KIDNEYS FOR HOMOTRANSPLANTATION IN CHILDREN [J].
FINE, RN ;
BRENNAN, LP ;
EDELBROC.HH ;
RIDDELL, H ;
STILES, Q ;
LIEBERMA.E .
JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1969, 210 (03) :477-&
[4]  
KOOTSTRA G, 1978, SURGERY, V83, P333
[5]  
MANAGADZE L G, 1981, International Urology and Nephrology, V13, P95, DOI 10.1007/BF02082078
[6]   RENAL-TRANSPLANTATION BETWEEN ADULTS AND CHILDREN - DIFFERENCES IN RENAL GROWTH [J].
SILBER, SJ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1974, 228 (09) :1143-1145
[7]  
SILBER SJ, 1976, ARCH SURG-CHICAGO, V111, P75
[8]  
VANDERVLIET JA, 1982, TRANSPLANT P, V14, P74
[9]   TRANSPLANTATION OF PEDIATRIC DONOR KIDNEYS TO ADULT RECIPIENTS - IS THERE A CRITICAL DONOR AGE [J].
WENGERTER, K ;
MATAS, AJ ;
TELLIS, VA ;
QUINN, T ;
SOBERMAN, R ;
VEITH, FJ .
ANNALS OF SURGERY, 1986, 204 (02) :172-175
[10]  
WETZELS JFM, 1986, CLIN NEPHROL, V25, P256