COUNTING ALGORITHMS FOR LINKAGE

被引：6

作者：

MORTON, NE

COLLINS, A

机构：

[1] Crc Research Group in Genetic Epidemiology, Department of Community Medicine, Southampton General Hospital, Southampton, Hampshire

来源：

ANNALS OF HUMAN GENETICS | 1990年 / 54卷

关键词：

D O I：

10.1111/j.1469-1809.1990.tb00365.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The Lander‐Green algorithm is algebraically different from the EM algorithm that maximizes likelihood. In our experience the numerical difference is very small. Since computations are no easier or convergence faster for the Lander–Green algorithm, there is no reason to prefer it to EM. As suggested by Green (personal communication), layering is advantageous. Occasional updating of the information weights might also be considered to accelerate mapping. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：103 / 106

页数：4

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