SEQUENCE STATISTICS RELIABLY PREDICT STABILIZING MUTATIONS IN A PROTEIN DOMAIN

被引:266
作者
STEIPE, B [1 ]
SCHILLER, B [1 ]
PLUCKTHUN, A [1 ]
STEINBACHER, S [1 ]
机构
[1] UNIV ZURICH, INST BIOCHEM, CH-8057 ZURICH, SWITZERLAND
关键词
PROTEIN STABILITY; IMMUNOGLOBULIN VARIABLE DOMAIN; POINT MUTATION; STABILITY PREDICTION; CANONICAL ENSEMBLE;
D O I
10.1006/jmbi.1994.1434
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:188 / 192
页数:5
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