CHANGES IN S-TYPE LECTIN LOCALIZATION IN NEUROBLASTOMA-CELLS (N1E115) UPON DIFFERENTIATION

被引：16

作者：

AVELLANAADALID, V

REBEL, G

CARON, M

CORNILLOT, JD

BLADIER, D

JOUBERTCARON, R

机构：

[1] CNRS, CTR NEUROCHIM, F-67084 STRASBOURG, FRANCE

[2] HOP AVICENNE, CENT BIOCHIM LAB, BOBIGNY, FRANCE

[3] UNIV PARIS NORD, LEONARD VINCI UFR SMBH, BIOCHIM & TECHNOL PROT LAB, F-93012 BOBIGNY, FRANCE

来源：

GLYCOCONJUGATE JOURNAL | 1994年 / 11卷 / 04期

关键词：

ENDOGENOUS LECTIN; NEUROBLASTOMA CELLS; DIFFERENTIATION; GLYCOCONJUGATES; IMMUNOCYTOCHEMISTRY;

D O I：

10.1007/BF00731200

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The distribution of a 14.4 kDa S-type lectin was examined in murine neuroblastoma cells, either undifferentiated or after differentiation induced by dibutyryl-cyclic adenosine monophosphate. In undifferentiated cells the immunoreactivity was detected extracellularly, associated with the plasma membrane and in bulges released into the extracellular milieu. Important modifications of the lectin localization were associated with the differentiation process that induced an increased cytosolic expression and a decreased externalization. Possible functions for the lectin expressed intracellularly in the differentiated cells are also considered.

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收藏

页码：286 / 291

页数：6

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