THE GENERATION OF INTENSITY-MODULATED FIELDS FOR CONFORMAL RADIOTHERAPY BY DYNAMIC COLLIMATION

被引:261
作者
CONVERY, DJ
ROSENBLOOM, ME
机构
[1] INST CANC RES,JOINT DEPT PHYS,SUTTON SM2 5PT,SURREY,ENGLAND
[2] ROYAL MARSDEN HOSP,SUTTON SM2 5PT,SURREY,ENGLAND
关键词
D O I
10.1088/0031-9155/37/6/012
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
An algorithm has been developed to calculate the collimator jaw motions required to generate intensity modulated field, for use in conformal radiotherapy. The dynamic technique allows arbitrary intensity profiles to be generated using a single unidirectional sweep of the collimators. The collimator jaws have independent motion, so that an aperture of variable width is scanned across thc field. The algorithm has the form of a constrained optimization problem and jaw motions are optimized such that the treatment time for the field at a given dose rate is minimized. The application and results of this technique are presented, and it is shown that this approach provides an efficient practical implementation of conformal radiotherapy plans based on the use of intensity-modulated fields. The technique can be extended to 3D treatment plans and fields through the use of computer-controlled multileaf collimators.
引用
收藏
页码:1359 / 1374
页数:16
相关论文
共 12 条
  • [1] BJARNGARD B, 1976, 5TH P INT C US COMP, P110
  • [2] METHODS OF IMAGE-RECONSTRUCTION FROM PROJECTIONS APPLIED TO CONFORMATION RADIOTHERAPY
    BORTFELD, T
    BURKELBACH, J
    BOESECKE, R
    SCHLEGEL, W
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 1990, 35 (10) : 1423 - 1434
  • [3] OPTIMIZATION OF STATIONARY AND MOVING BEAM RADIATION-THERAPY TECHNIQUES
    BRAHME, A
    [J]. RADIOTHERAPY AND ONCOLOGY, 1988, 12 (02) : 129 - 140
  • [4] BRAHME A, 1987, 9TH P INT C COMP RAD, P227
  • [5] A COMPUTATIONAL SOLUTION OF THE INVERSE PROBLEM IN RADIATION-THERAPY TREATMENT PLANNING
    CENSOR, Y
    ALTSCHULER, MD
    POWLIS, WD
    [J]. APPLIED MATHEMATICS AND COMPUTATION, 1988, 25 (01) : 57 - 87
  • [6] Gill P. E., 1981, PRACTICAL OPTIMIZATI
  • [7] A UNIFIED APPROACH TO THE OPTIMIZATION OF BRACHYTHERAPY AND EXTERNAL BEAM DOSIMETRY
    HOLMES, T
    MACKIE, TR
    SIMPKIN, D
    RECKWERDT, P
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1991, 20 (04): : 859 - 873
  • [8] SHAPING OF ARBITRARY DOSE DISTRIBUTIONS BY DYNAMIC MULTILEAF COLLIMATION
    KALLMAN, P
    LIND, B
    EKLOF, A
    BRAHME, A
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 1988, 33 (11) : 1291 - 1300
  • [9] KIJEWSKI P K, 1978, Medical Physics (Woodbury), V5, P426, DOI 10.1118/1.594440
  • [10] SEMI-AUTOMATED RADIOTHERAPY TREATMENT PLANNING WITH A MATHEMATICAL-MODEL TO SATISFY TREATMENT GOALS
    POWLIS, WD
    ALTSCHULER, MD
    CENSOR, Y
    BUHLE, EL
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1989, 16 (01): : 271 - 276