MULTIPLE COLUMN SOLID-PHASE GLYCOPEPTIDE SYNTHESIS

被引：31

作者：

PETERS, S

BIELFELDT, T

MELDAL, M

BOCK, K

PAULSEN, H

机构：

[1] UNIV HAMBURG,INST ORGAN CHEM,MARTIN LUTHER KING PLATZ 6,W-2000 HAMBURG 13,GERMANY

[2] CARLSBERG LAB,DEPT CHEM,DK-2500 COPENHAGEN,DENMARK

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 38期

关键词：

D O I：

10.1016/S0040-4039(00)93429-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The simultaneous synthesis of 40 different alpha-linked O-glycopeptides from human intestinal mucin, and porcine submaxillary gland mucin in a manual multiple, column peptide synthesizer using the new glycosylamino acid building blocks N-alpha-Fmoc-Ser(Ac3-alpha-D-GalpNAc)-OPfp (3) and N-alpha-Fmoc-Thr(Ac3-alpha-D-GalpNAc)-OPfp (4) is described.

引用

收藏

页码：5067 / 5070

页数：4

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