SIMPLE SYNTHESES OF 3,4-DIDEOXY-OCT-2-ULOSONIC ACIDS

被引：11

作者：

SHING, TKM

机构：

[1] Department of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(00)91608-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bisacetonated aldehydo-D-arabinose has been converted by three consecutive reactions (Wittig reaction, catalytic hydrogenation, and hydrolysis) into 3,4-dideoxy-D-arabino-oct-2-ulosonic acid (4-deoxy-KDO), isolated as its calcium salt in an overall yield of 37% from D-arabinose. Likewise reactions of D-xylose gave calcium 3,4-dideoxy-D-xylo-oct-2-ulosonate in an overall yield of 34%.

引用

页码：1307 / 1308

页数：2

共 12 条

[1]

ALLEN NE, 1985, ANNU REP MED CHEM, V20, P155

[2]

ANDERSON L, 1983, ACS S SERIES, V231

[3] A 2-DEOXY ANALOG OF KDO AS THE 1ST INHIBITOR OF THE ENZYME CMP-KDO SYNTHETASE [J].