IN-VITRO ANTIMYCOPLASMAL ACTIVITY OF FLURITHROMYCIN

被引:4
作者
FURNERI, PM [1 ]
BISIGNANO, G [1 ]
CERNIGLIA, G [1 ]
TEMPERA, G [1 ]
NICOLETTI, G [1 ]
机构
[1] UNIV MESSINA,DEPT PHARMACOBIOL,I-98100 MESSINA,ITALY
关键词
D O I
10.1093/jac/35.1.161
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The in vitro activity of flurithromycin, a (14)-membered macrolide drug, was found to be similar to that of erythromycin against 41 strains of Mycoplasma spp. and 100 strains of Ureaplasma urealyticum. All 28 strains of Mycoplasma hominis were uniformly resistant to both macrolides with MICs > 256 mg/L, U. urealyticum showed intermediate resistance with MIC(50)s of 0.5 and 1 mg/L for erythromycin and flurithromycin, respectively, whereas the ten strains of Mycoplasma pneumonia were susceptible to less than or equal to 0.03 mg/L of both macrolides.
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收藏
页码:161 / 165
页数:5
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