THE BEHAVIOR OF CELLS FROM THE DISTAL TIPS OF QUAIL WING BUDS WHEN GRAFTED BACK INTO CHICK WINGS AFTER MICROMASS CULTURE

被引：4

作者：

COTTRILL, CP ^{[1
]}

CRAWLEY, A ^{[1
]}

TICKLE, C ^{[1
]}

机构：

[1] UNIV COLL & MIDDLESEX SCH MED, DEPT ANAT & DEV BIOL, WINDEYER BLDG, CLEVELAND ST, LONDON W1P 6DB, ENGLAND

来源：

CELL DIFFERENTIATION AND DEVELOPMENT | 1990年 / 29卷 / 01期

关键词：

Chick limb; Chondrogenesis; Differentiation;

D O I：

10.1016/0922-3371(90)90025-R

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In high density culture, cells from distal tips of developing limb buds differentiate into a continuous cartilage sheet, rich in type II collagen. When grafted back into limb buds, cells cultured for a short time differentiate into cartilage and a wide range of other connective tissues, whereas cells taken from older cultures give rise only to cartilage and perichondrium. Grafts placed distally give rise to more cell types than grafts placed proximally. The results strongly suggest that chondrogenesis in culture is the result of removing the signals that pattern differentiation within the limb bud. © 1990.

引用

收藏

页码：67 / 80

页数：14

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