DIFFERENTIATION OF LEYDIG-CELL PRECURSORS INVITRO - A ROLE FOR ANDROGEN

被引：128

作者：

HARDY, MP

KELCE, WR

KLINEFELTER, GR

EWING, LL

机构：

[1] US EPA,HLTH EFFECTS RES LAB,RES TRIANGLE PK,NC 27711

[2] US EPA,NORTHROP SERV INC,RES TRIANGLE PK,NC 27711

来源：

ENDOCRINOLOGY | 1990年 / 127卷 / 01期

关键词：

D O I：

10.1210/endo-127-1-488

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

An enriched fraction of mesenchymal-like cells was isolated from the testes of 21 day old rats. Testosterone production (ng/106 cells · 24 hours) by these cells when cultured in vitro was measured by radioimmunoassay of HPLC-purified extracts of culture medium. In the presence of LH + DHT there was a significant increase in testosterone secretion from 22 ± 10 ng after day 1 of culture to 284 ± 75 ng on day 3. © 1990 by The Endocrine Society.

引用

页码：488 / 490

页数：3

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[2]

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[3]

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[4]

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