INSULIN RAPIDLY INCREASES DIACYLGLYCEROL BY ACTIVATING DENOVO PHOSPHATIDIC-ACID SYNTHESIS

被引：213

作者：

FARESE, RV

KONDA, TS

DAVIS, JS

STANDAERT, ML

POLLET, RJ

COOPER, DR

机构：

[1] UNIV S FLORIDA,COLL MED,DEPT INTERNAL MED,TAMPA,FL 33612

[2] UNIV S FLORIDA,COLL MED,DEPT BIOCHEM,TAMPA,FL 33612

来源：

SCIENCE | 1987年 / 236卷 / 4801期

关键词：

D O I：

10.1126/science.3107122

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：586 / 589

页数：4

共 21 条

[1] AMBLER SK, 1984, MOL PHARMACOL, V26, P405
[2] RAPID FORMATION OF DIACYLGLYCEROL FROM PHOSPHATIDYLCHOLINE - A PATHWAY FOR GENERATION OF A 2ND MESSENGER
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (18) : 6785 - 6789
[3] COOPER DR, 1987, J BIOL CHEM, V262, P3633
[4] MEASUREMENT OF FLOW OF CARBON ATOMS FROM GLUCOSE AND GLYCOGEN GLUCOSE TO GLYCERIDE GLYCEROL AND GLYCEROL IN RAT HEART AND EPIDIDYMAL ADIPOSE TISSUE
DENTON, RM
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[J]. BIOCHEMICAL JOURNAL, 1967, 104 (02) : 423 - &
[5] THE MECHANISM OF ACTION OF INSULIN ON PHOSPHOLIPID-METABOLISM IN RAT ADIPOSE-TISSUE - REQUIREMENT FOR PROTEIN-SYNTHESIS AND A CARBOHYDRATE SOURCE, AND RELATIONSHIP TO ACTIVATION OF PYRUVATE-DEHYDROGENASE
FARESE, RV
FARESE, RV
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[J]. DIABETES, 1984, 33 (07) : 648 - 655
[6] EFFECTS OF ADRENOCORTICOTROPIN AND CYCLOHEXIMIDE ON ADRENAL DIGLYCERIDE KINASE
FARESE, RV
SABIR, MA
LARSON, RE
[J]. BIOCHEMISTRY, 1981, 20 (21) : 6047 - 6051
[7] FURTHER EVIDENCE IMPLICATING DIACYLGLYCEROL GENERATION AND PROTEIN-KINASE-C ACTIVATION IN AGONIST-INDUCED INCREASES IN GLUCOSE-UPTAKE - INSULIN-LIKE EFFECTS OF PHENYLEPHRINE IN BC3H-1 MYOCYTES
FARESE, RV
ROSIC, N
STANDAERT, M
BABISCHKIN, J
COOPER, DR
DAVIS, JS
POLLET, RJ
[J]. DIABETES, 1986, 35 (09) : 951 - 957
[8] PHORBOL ESTER PROVOKES INSULIN-LIKE EFFECTS ON GLUCOSE-TRANSPORT, AMINO-ACID UPTAKE, AND PYRUVATE-DEHYDROGENASE ACTIVITY IN BC3H-1 CULTURED MYOCYTES
FARESE, RV
STANDAERT, ML
BARNES, DE
DAVIS, JS
POLLET, RJ
[J]. ENDOCRINOLOGY, 1985, 116 (06) : 2650 - 2655
[9] FARESE RV, 1982, J BIOL CHEM, V257, P4042
[10] THE DENOVO PHOSPHOLIPID EFFECT OF INSULIN IS ASSOCIATED WITH INCREASES IN DIACYLGLYCEROL, BUT NOT INOSITOL PHOSPHATES OR CYTOSOLIC CA-2+
FARESE, RV
DAVIS, JS
BARNES, DE
STANDAERT, ML
BABISCHKIN, JS
HOCK, R
ROSIC, NK
POLLET, RJ
[J]. BIOCHEMICAL JOURNAL, 1985, 231 (02) : 269 - 278

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