VENTRICULAR SOMATOSTATIN-LIKE IMMUNOREACTIVITY IN PATIENTS WITH BASAL GANGLIA DISEASE

被引：18

作者：

CRAMER, H

WOLF, A

RISSLER, K

WEIGEL, K

OSTERTAG, C

机构：

[1] UNIV FREIBURG, DEPT NEUROL & CLIN NEUROPHYSIOL, HANSASTR 9, D-7800 FREIBURG, FED REP GER

[2] UNIV FREIBURG, DEPT STEREOTAXY & NUCL MED, D-7800 FREIBURG, FED REP GER

来源：

JOURNAL OF NEUROLOGY | 1985年 / 232卷 / 04期

关键词：

D O I：

10.1007/BF00313783

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The concentrations of somatostatin-like immunoreactivity (SLI) in lateral ventricular fluid of patients with extrapyramidal motor disease were determined by specific radio-immunoassay. Mean SLI levels were significantly lower in patients with Parkinson''s disease (mean .+-. SEM; 42.9 .+-. 2.9 fmol/ml) and in patients with dystonic syndromes (39.4 .+-. 3.2) than in patients with benign essential tremor (65.3 .+-. 9.7). The lowest levels were found in patients with athetosis (34.7 .+-. 5.4). In parkinsonian patients somatostatin levels correlated with the degree of akinesia, rigidity and autonomic disturbances.

引用

页码：219 / 222

页数：4

共 37 条

[1]

ARIMURA A, 1975, P SOC EXP BIOL MED, V148, P784

[2] SOMATOSTATIN IS INCREASED IN THE BASAL GANGLIA IN HUNTINGTON DISEASE [J].