COSTS AND HEALTH CONSEQUENCES OF CHOLESTEROL SCREENING FOR ASYMPTOMATIC OLDER AMERICANS

被引:46
作者
GARBER, AM
LITTENBERG, B
SOX, HC
WAGNER, JL
GLUCK, M
机构
[1] STANFORD UNIV, MED CTR, SCH MED, DIV GEN INTERNAL MED, STANFORD, CA 94305 USA
[2] VET AFFAIRS MED CTR, PALO ALTO, CA USA
[3] DARTMOUTH COLL, HITCHCOCK MED CTR, DEPT MED, HANOVER, NH 03756 USA
[4] US CONGRESS, OFF TECHNOL ASSESSMENT, WASHINGTON, DC USA
关键词
D O I
10.1001/archinte.151.6.1089
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
To predict the consequences of cholesterol screening among elderly Americans who do not have symptoms of heart disease, we explore the cost implications of a cholesterol screening program, evaluate evidence linking hypercholesterolemia to coronary heart disease and mortality in the elderly, and describe the likely effects of therapy of hypercholesterolemia. According to our calculations, if all Americans 65 years of age and older adhered to a cholesterol screening program similar to the one proposed by the National Cholesterol Education Program, minimum annual expenditures for screening and treatment would be between $1.6 billion and $16.8 billion, depending on the effectiveness of diet and the cost of the medications used to treat hypercholesterolemia. There is no direct evidence that this program would lessen overall morbidity or extend the lives of elderly Americans.
引用
收藏
页码:1089 / 1095
页数:7
相关论文
共 54 条
  • [1] AGNER E, 1983, ACTA MED SCAND, V214, P33
  • [2] Agner E, 1985, Acta Med Scand Suppl, V696, P3
  • [3] CHOLESTEROL AND MORTALITY - 30 YEARS OF FOLLOW-UP FROM THE FRAMINGHAM-STUDY
    ANDERSON, KM
    CASTELLI, WP
    LEVY, D
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1987, 257 (16): : 2176 - 2180
  • [4] DIET, LIPOPROTEINS, AND THE PROGRESSION OF CORONARY ATHEROSCLEROSIS - THE LEIDEN INTERVENTION TRIAL
    ARNTZENIUS, AC
    KROMHOUT, D
    BARTH, JD
    REIBER, JHC
    BRUSCHKE, AVG
    BUIS, B
    VANGENT, CM
    KEMPENVOOGD, N
    STRIKWERDA, S
    VANDERVELDE, EA
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1985, 312 (13) : 805 - 811
  • [5] ISCHEMIC HEART-DISEASE RISK-FACTORS AFTER AGE 50
    BARRETTCONNOR, E
    SUAREZ, L
    KHAW, KT
    CRIQUI, MH
    WINGARD, DL
    [J]. JOURNAL OF CHRONIC DISEASES, 1984, 37 (12): : 903 - 908
  • [6] BASINSKI A, 1989, DETECTION MANAGEMENT
  • [7] IS ELEVATED SERUM-CHOLESTEROL LEVEL A RISK FACTOR FOR CORONARY HEART-DISEASE IN THE ELDERLY
    BENFANTE, R
    REED, D
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1990, 263 (03): : 393 - 396
  • [8] BENEFICIAL-EFFECTS OF COMBINED COLESTIPOL-NIACIN THERAPY ON CORONARY ATHEROSCLEROSIS AND CORONARY VENOUS BYPASS GRAFTS
    BLANKENHORN, DH
    NESSIM, SA
    JOHNSON, RL
    SANMARCO, ME
    AZEN, SP
    CASHINHEMPHILL, L
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1987, 257 (23): : 3233 - 3240
  • [9] 15 YEAR MORTALITY IN CORONARY DRUG PROJECT PATIENTS - LONG-TERM BENEFIT WITH NIACIN
    CANNER, PL
    BERGE, KG
    WENGER, NK
    STAMLER, J
    FRIEDMAN, L
    PRINEAS, RJ
    FRIEDEWALD, W
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1986, 8 (06) : 1245 - 1255
  • [10] CARLSON LA, 1972, LANCET, V1, P865