HEPARIN AND SPINAL OR EPIDURAL-ANESTHESIA - CLINICAL DECISION-MAKING

被引:36
作者
SCHWANDER, D
BACHMANN, F
机构
[1] Service d'Anesthésiologie-Réanimation
[2] Division d'Hématologie, CHUV
来源
ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION | 1991年 / 10卷 / 03期
关键词
D O I
10.1016/S0750-7658(05)80835-4
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
The incidence of thromboembolism justifies prophylactic measures, the most efficient of which is the use of heparin. However this agent may be responsible for haemorrhagic complications during regional anaesthesia. The risk of bleeding in a poorly accessible area, e.g. the epidural space, the brachial plexus sheet, the space behind the eyeball, is one of the concerns of anaesthetists. A review of case reports of haemorrhagic complications of spinal anaesthesia shows that the risk of bleeding or of spinal haematoma is very low. In fact, a blood or epidural vessel is punctured in 2.8 to 11.5% of cases of epidural anaesthesia, without any sequelae. Some authors suggest that low molecular weight heparin may be given to patients before spinal anaesthesia. In all cases, patients should be carefully assessed before, during and after the procedure, clinically and biologically. The absolute contra-indications to these techniques are a refusal by the patient, an uncooperative patient, severe coagulation disorders, untreated hypovolaemia, infection of the puncture site, severe generalized infection, and raised intracranial pressure. Decision as to whether a regional anaesthetic technique should be used in a particular patient who is under anticoagulant treatment, or who is to receive such a treatment intra or postoperatively, must be made on an individual basis. The risk of thromboembolism must be weighted against the risk of haemorrhagic complications. Unfortunately, in the absence of relevant studies, anaesthetists can only rely on their clinical judgment.
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收藏
页码:284 / 296
页数:13
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共 73 条
[1]  
Adriani, Naragi, Paraplegia associated with epidural anesthesia, Southern Med J, 79, pp. 1350-1355, (1986)
[2]  
Allemann, Gerber, Gruber, Rückenmarksnahe Anaesthesie und subkutan verabreichtes low-dose Heparin-Dihydergot zur Thromboembolieprophylaxe, Anaesthesist, 32, pp. 80-83, (1983)
[3]  
Amrein, Ellman, Harris, Aspirin-induced prolongation of bleeding time and perioperative blood loss, JAMA, 245, pp. 1825-1828, (1981)
[4]  
Ang, Kohn, Delefosse, Galet, Goldfarb, Jolis, Incidence des complications locales après anesthésie rachidienne chez les patients traités par héparine de bas poids moléculaire, Ann Fr Anesth Réanim, 8, (1989)
[5]  
Bachmann, Anticoagulants et agents thrombolytiques (pp 267–286), Pharmacologie, des concepts fondamentaux aux applications thérapeutiques, (1988)
[6]  
Baron, LaRaja, Rossi, Atkinson, Continuous epidural analgesia in the heparinized vascular surgical patient : a retrospective review of 912 patients, J Vasc Surg, 6, pp. 144-146, (1987)
[7]  
Barre, Pfister, Potron, Droulle, Baudrillard, Barbier, Kehr, Efficacité et tolérance comparée du Kabi 2165 et de l'héparine standard dans la prévention des thromboses veineuses profondes au cours des prothèses totales de hanche, J Mal Vasc, 12, pp. 90-95, (1987)
[8]  
Bergqvist, Matzsch, Burmark, Frisell, Guilbaud, Hallbook, Horn, Lindhagen, Ljungner, Ljungstrom, Onarheim, Risberg, Torngrent, Ortenwall, Low molecular weight heparin given the evening before surgery compared with conventional low-dose heparin in prevention of thrombosis, Br J Surg, 75, pp. 888-891, (1988)
[9]  
Blery, Faut-il dresser un bilan de coagulation avant une anesthésie locorégionale chez un sujet ASA 1 ?, Ann Fr Anesth Réanim, 9, pp. 371-374, (1990)
[10]  
Bready, Smith, Decision making in anesthesiology (pp 236–237), (1987)