PEAK VELOCITY OF THE OUTFLOW TRACT OF THE AORTA - CORRELATIONS WITH ACID-BASE STATUS AND OXYGENATION OF THE GROWTH-RETARDED FETUS

被引:22
作者
FERRAZZI, E
BELLOTTI, M
MARCONI, A
FLISI, L
BARBERA, A
PARDI, G
机构
[1] Department of Obstetrics and Gynecology, San Paolo Biomedical Sciences Institute, University of Milan
关键词
D O I
10.1016/0029-7844(95)00021-I
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To correlate the peak velocities of the aortic outflow tract of growth-retarded fetuses with fetal acid base status and oxygenation measured in utero. Methods: Thirty-one growth-retarded fetuses with abnormal umbilical pulsatility index (PI) measurements underwent fetal blood sampling. Blood pH, carbon dioxide pressure (PCO2), oxygen pressure (PO2), oxygen saturation, lactate concentration, and hemoglobin concentration were measured. Using color Doppler equipment, we measured the peak velocities of the outflow tract of the aorta, pulmonary artery, and ductus arteriosus before fetal blood sampling. Results: The peak velocities measured in the outflow tract of the aorta, pulmonary artery, and ductus were significantly lower in growth-retarded fetuses than in 140 normal fetuses of comparable weight. The correlation observed between pulmonic and aortic peak velocities was significant (r = 0.84), as was that between pulmonic and ductal peak velocitied (r = 0.74). Growth-retarded fetuses with abnormal aortic peak velocities had significantly lower values of pO(2), oxygen content and pH, and had higher lactate concentration and PCO2 than did growth-retarded fetuses with normal peak velocities. Estimated fetal weight and umbilical PI (mean +/- standard deviation) were not significantly different in these two groups. Moreover, significant direct correlations were found between proximal aortic peak velocities and lactate concentrations (correlation coefficient 0.71, P <.0001) and O-2 content (P <.02, r = 0.42). Conclusion: For growth-retarded fetuses, Doppler peak velocity in these vessels is significantly lower than in normal fetuses of comparable weight. Aortic, pulmonic, and ductal peak velocity correlated significantly. Growth-retarded fetuses with abnormally low peak velocity in the outflow tract of the aorta have a higher risk of acidemia and hypoxia than those with normal velocities.
引用
收藏
页码:663 / 668
页数:6
相关论文
共 14 条
  • [1] ALGAZALI W, 1989, BRIT J OBSTET GYNAEC, V96, P697
  • [2] ROLE OF UMBILICAL DOPPLER VELOCIMETRY IN THE BIOPHYSICAL ASSESSMENT OF THE GROWTH-RETARDED FETUS - ANSWERS FROM NEONATAL MORBIDITY AND MORTALITY
    FERRAZZI, E
    VEGNI, C
    BELLOTTI, M
    BORBONI, A
    DELLAPERUTA, S
    BARBERA, A
    [J]. JOURNAL OF ULTRASOUND IN MEDICINE, 1991, 10 (06) : 309 - 315
  • [3] JENSEN A, 1991, J DEV PHYSIOL, V15, P309
  • [4] KAMITOMO M, 1992, AM J PHYSIOL, V262, P399
  • [5] FETAL CENTRAL BLOOD-CIRCULATION IN THE 3RD TRIMESTER OF NORMAL-PREGNANCY - A LONGITUDINAL-STUDY .1. AORTIC AND UMBILICAL BLOOD-FLOW
    LINGMAN, G
    MARSAL, K
    [J]. EARLY HUMAN DEVELOPMENT, 1986, 13 (02) : 137 - 150
  • [6] Parazzini F, 1991, Ann Ostet Ginecol Med Perinat, V112, P203
  • [7] PARDI G, 1993, NEW ENGL J MED, V28, P692
  • [8] RELATION OF FETAL BLOOD-GASES AND DATA FROM COMPUTER-ASSISTED ANALYSIS OF FETAL HEART-RATE PATTERNS IN SMALL FOR GESTATION FETUSES
    RIBBERT, LSM
    SNIJDERS, RJM
    NICOLAIDES, KH
    VISSER, GHA
    [J]. BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1991, 98 (08): : 820 - 823
  • [9] DOPPLER ECHOCARDIOGRAPHIC ASSESSMENT OF ATRIOVENTRICULAR VELOCITY WAVEFORMS IN NORMAL AND SMALL-FOR-GESTATIONAL-AGE FETUSES
    RIZZO, G
    ARDUINI, D
    ROMANINI, C
    MANCUSO, S
    [J]. BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1988, 95 (01): : 65 - 69
  • [10] FETAL CARDIAC-FUNCTION IN INTRAUTERINE GROWTH-RETARDATION
    RIZZO, G
    ARDUINI, D
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1991, 165 (04) : 876 - 882