A CONVENIENT SYNTHESIS OF PYRIDAZINE-3,4-DICARBOXYLIC ACID BY A HETERO-DIELS-ALDER REACTION

被引：18

作者：

VORS, JP

机构：

[1] Centre de Recherches de la Dargoire, Lyon, 69263

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1990年 / 27卷 / 03期

关键词：

D O I：

10.1002/jhet.5570270319

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient route to prepare unsubstituted pyridazine‐3,4‐dicarboxylic acid on a preparative scale is described. The synthesis involves a hetero Diels‐Alder reaction between a new 1,2‐diaza‐1,3‐diene and ethyl vinyl ether and oxidation of the intermediate 1,4,5,6‐tetrahydropyridazine as the key step. Copyright © 1990 Journal of Heterocyclic Chemistry

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页码：579 / 582

页数：4

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