GENES, ENZYMES AND COENZYMES OF QUEUOSINE BIOSYNTHESIS IN PROKARYOTES

被引：37

作者：

SLANY, RK

KERSTEN, H

机构：

[1] Institut für Biochemie, Universität Erlangen, 91054 Erlangen

来源：

BIOCHIMIE | 1994年 / 76卷 / 12期

关键词：

QUEUOSINE; TRANSFER-RNA MODIFICATION; QUEA; S-ADENOSYLMETHIONIN; TRANSFER-RNA RIBOSYLTRANSFERASE-ISOMERASE; TGT; TRANSFER-RNA GUANINE TRANSGLYCOSYLASE;

D O I：

10.1016/0300-9084(94)90047-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In almost all known tRNAs that are specific for Asp, Asn, His or Tyr the wobble position of the anticodon is occupied by the hypermodified tRNA nucleoside queuosine. This unusual deazaguanine derivative is synthesised only in eubacteria. The biosynthesis, as investigated in Escherichia coli, is accomplished in four steps involving many unprecedented enzymatic reactions.

引用

页码：1178 / 1182

页数：5

共 26 条

[1]

BROWN GM, 1987, ESCHERICHIA COLI SAL

[2]

CHONG S, 1994, FASEB J, V8, pA1410

[3] TRANSFER RNA-GUANINE TRANSGLYCOSYLASE FROM ESCHERICHIA-COLI - GROSS TRANSFER-RNA STRUCTURAL REQUIREMENTS FOR RECOGNITION [J].