HYBRIDIZATION PROPERTIES OF THE 5-METHYL-ISOCYTIDINE ISOGUANOSINE BASE-PAIR IN SYNTHETIC OLIGODEOXYNUCLEOTIDES

被引：8

作者：

HORN, T

CHANG, CA

COLLINS, ML

机构：

[1] Nucleic Acids Systems, Chiron Corp., Emeryville

来源：

NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 3-5期

关键词：

D O I：

10.1080/15257779508012525

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The hybridization properties of the 5-methyl-isocytidine / isoguanosine base pair in synthetic oligodeoxynucleotides have been investigated. The 5-methyl-isocytidine / isoguanosine base pair has been determined to be isoenergetic with the cytidine / guanosine, and each base can effectively discriminate mismatches.

引用

页码：1023 / 1026

页数：4

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