SEXUAL-BEHAVIOR, SEXUALLY-TRANSMITTED DISEASES, AND RISK OF CERVICAL-CANCER

被引：51

作者：

STONE, KM

ZAIDI, A

ROSEROBIXBY, L

OBERLE, MW

REYNOLDS, G

LARSEN, S

NAHMIAS, AJ

LEE, FK

SCHACHTER, J

GUINAN, ME

机构：

[1] Division of Sexually Transmitted Disease/HIV Prevention, National Center for Prevention Services, Atlanta, GA

[2] Asociación Demográfica Costarricense, San José

[3] Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Atlanta, GA

[4] Division of Sexually Transmitted Diseases, Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, GA

[5] Department of Pediatrics, Division of Pediatric Infectious Diseases, Epidemiology and Immunology, Emory University School of Medicine, Atlanta, GA

[6] Departments of Epidemiology and Laboratory Medicine, University of California, San Francisco, CA

来源：

EPIDEMIOLOGY | 1995年 / 6卷 / 04期

关键词：

CERVICAL CANCER; SEXUALLY TRANSMITTED DISEASES; SEXUAL BEHAVIOR; HERPES SIMPLEX VIRUS; CHLAMYDIA; PARITY; ORAL CONTRACEPTIVES;

D O I：

10.1097/00001648-199507000-00014

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

To explore sexually transmitted diseases and sexual behavior as risk factors for cervical cancer, we analyzed data from a population-based case-control study of breast and cervical cancer in Costa Rica. Data from 415 cases of cervical carcinoma in situ, 149 cases of invasive cervical cancer, and 764 controls were included in the analysis. Multivariate analysis showed that lifetime number of sex partners, first intercourse before age 15 years, number of livebirths, herpes simplex virus type 2 seropositivity, and serologic evidence of previous chlamydial infection were predictors of carcinoma in situ. Serologic evidence of previous syphilis was not associated with carcinoma in situ. Predictors for invasive cervical cancer included lifetime number of sex partners, first intercourse before age 15 years, number of livebirths, serologic evidence of previous syphilis, herpes simplex type 2 infection, and chlamydial infection. Cigarette smoking, socioeconomic status, self-reported history of sexually transmitted diseases, and douching were not associated with either carcinoma in situ or invasive cervical cancer.

引用

页码：409 / 414

页数：6

共 47 条

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