RATJADON - A NEW ANTIFUNGAL COMPOUND FROM SORANGIUM-CELLULOSUM (MYXOBACTERIA) - PRODUCTION, PHYSICOCHEMICAL, AND BIOLOGICAL PROPERTIES

被引:42
作者
GERTH, K [1 ]
SCHUMMER, D [1 ]
HOFLE, G [1 ]
IRSCHIK, H [1 ]
REICHENBACH, H [1 ]
机构
[1] GBF,GESELL BIOTECHNOL FORSCH GMBH,NATURSTOFFCHEM ABT,D-38124 BRAUNSCHWEIG,GERMANY
关键词
D O I
10.7164/antibiotics.48.973
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
An antifungal activity, ratjadon, was detected in the culture broth of Sorangium cellulosum (Myxococcales) strain So ce360. The metabolite was quantitatively bound to the adsorber resin XAD-16, which was added to the medium at the beginning of the fermentation. The antibiotic spectrum was narrow, but some important phytopathogenic fungi, especially species of Oomycetes, were inhibited at very low concentrations.
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页码:973 / 976
页数:4
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