H-1-AND C-13-NMR SPECTRA OF CAMPTOTHECIN AND DERIVATIVES

被引：14

作者：

EZELL, EL ^{[1
]}

SMITH, LL ^{[1
]}

机构：

[1] UNIV TEXAS,MED BRANCH,DEPT HUMAN BIOL CHEM & GENET,GALVESTON,TX 77550

来源：

JOURNAL OF NATURAL PRODUCTS | 1991年 / 54卷 / 06期

关键词：

D O I：

10.1021/np50078a025

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

H-1- and C-13 spectra of camptothecin, 9- and 12-nitrocamptothecins, and 10,11-methylenedioxycamptothecin are assigned from 1D and 2D nmr data.

引用

页码：1645 / 1650

页数：6

共 18 条

[1] 2-DIMENSIONAL SPECTROSCOPY - APPLICATION TO NUCLEAR MAGNETIC-RESONANCE [J].

AUE, WP ;

BARTHOLDI, E ;

ERNST, RR .

JOURNAL OF CHEMICAL PHYSICS, 1976, 64 (05) :2229-2246

[2] HETERONUCLEAR CHEMICAL-SHIFT CORRELATION BY FULLY COUPLED PHASE-SENSITIVE TWO-DIMENSIONAL NMR, A ROBUST EXPERIMENT [J].

BAIN, AD .

JOURNAL OF MAGNETIC RESONANCE, 1988, 77 (01) :125-133

[3] MLEV-17-BASED TWO-DIMENSIONAL HOMONUCLEAR MAGNETIZATION TRANSFER SPECTROSCOPY [J].

BAX, A ;

DAVIS, DG .

JOURNAL OF MAGNETIC RESONANCE, 1985, 65 (02) :355-360

[4] AN IMPROVED METHOD FOR HETERONUCLEAR CHEMICAL-SHIFT CORRELATION BY TWO-DIMENSIONAL NMR [J].

BAX, A ;

MORRIS, GA .

JOURNAL OF MAGNETIC RESONANCE, 1981, 42 (03) :501-505

[5]

Cai J-C., 1983, ALKALOIDS CHEM PHARM, VVol. 21, P101

[6] DNA TOPOISOMERASE-I TARGETED CHEMOTHERAPY OF HUMAN-COLON CANCER IN XENOGRAFTS [J].

GIOVANELLA, BC ;

STEHLIN, JS ;

WALL, ME ;

WANI, MC ;

NICHOLAS, AW ;

LIU, LF ;

SILBER, R ;

POTMESIL, M .

SCIENCE, 1989, 246 (4933) :1046-1048

[7] PLANT ANTI-CANCER AGENTS .10. ISOLATION OF CAMPTOTHECIN AND 9-METHOXYCAMPTOTHECIN FROM ERVATAMIA-HEYNEANA [J].

GUNASEKERA, SP ;

BADAWI, MM ;

CORDELL, GA ;

FARNSWORTH, NR ;

CHITNIS, M .

JOURNAL OF NATURAL PRODUCTS, 1979, 42 (05) :475-477

[8]

HSIANG YH, 1989, CANCER RES, V49, P4385

[9] BIOSYNTHESIS OF CAMPTOTHECIN .1. DEFINITION OF OVERALL PATHWAY ASSISTED BY C-13 NUCLEAR MAGNETIC-RESONANCE ANALYSIS [J].

HUTCHINSON, CR ;

HECKENDORF, AH ;

DADDONA, PE ;

HAGAMAN, E ;

WENKERT, E .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1974, 96 (17) :5609-5611

[10] CAMPTOTHECIN - CHEMISTRY, BIOGENESIS AND MEDICINAL CHEMISTRY [J].

HUTCHINSON, CR .

TETRAHEDRON, 1981, 37 (06) :1047-1065

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