PALLADIUM-CATALYZED VINYLATION OF 4-BROMO-4'-HYDROXYBIPHENYL

被引：11

作者：

KELKAR, AA ^{[1
]}

HANAOKA, T ^{[1
]}

KUBOTA, Y ^{[1
]}

SUGI, Y ^{[1
]}

机构：

[1] NATL INST MAT & CHEM RES,TSUKUBA,IBARAKI 305,JAPAN

来源：

JOURNAL OF MOLECULAR CATALYSIS | 1994年 / 88卷 / 02期

关键词：

BASE EFFECTS; BIPHENYL; HECK REACTION; PALLADIUM CATALYST; PHOSPHINE LIGAND; VINYLATION;

D O I：

10.1016/0304-5102(93)E0275-L

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Vinylation of 4-bromo-4'-hydroxybiphenyl and ethyl acrylate using Pd(OAc)2/PPh3 catalyst was studied. Ethyl 4-(4'-hydroxyphenyl) cinnamate was formed as the vinylation product, while, 4-hydroxybiphenyl and ethyl cinnamate were formed as side products. The results of the effects of phosphine structure and amount showed ethyl cinnamate was formed by the cleavage of the P-Ph bond of PPh3. Activity and selectivity of vinylation were highly improved with the use of inorganic bases and ethyl 4-(4'-hydroxyphenyl) cinnamate was formed in the yield over 99%.

引用

页码：L113 / L116

页数：4

共 8 条

[1] PALLADIUM-CATALYZED ARYLATION OF UNSYMMETRICAL OLEFINS - BIDENTATE PHOSPHINE LIGAND CONTROLLED REGIOSELECTIVITY [J].