IMMUNOCYTOCHEMICAL STUDY OF THE RELATIONS OF ACETYLCHOLINESTERASE, ENKEPHALIN-RELATED, SUBSTANCE-P-RELATED, CHOLINE ACETYLTRANSFERASE-RELATED AND CALCITONIN GENE-RELATED PEPTIDE-IMMUNOREACTIVE STRUCTURES IN THE VENTRAL HORN OF RAT SPINAL-CORD

被引：23

作者：

HIETANEN, M ^{[1
]}

PELTOHUIKKO, M ^{[1
]}

RECHARDT, L ^{[1
]}

机构：

[1] UNIV TAMPERE,DEPT BIOMED SCI,BOX 607,SF-33101 TAMPERE,FINLAND

来源：

HISTOCHEMISTRY | 1990年 / 93卷 / 05期

关键词：

D O I：

10.1007/BF00266403

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Calcitonin gene-related peptide (CGRP)-like immunoreactivity was localized immunocytochemically in the large motoneurons in the ventral horn of rat spinal cord. Using fluorescence double-labelling substance P (SP)-immunoreactive nerve fibres were found to surround both the CGRP-positive and negative motoneurons, whereas enkephalin (ENK)-immunoreactive fibres surrounded mainly CGRP-negative cells. All CGRP-like immunoreactive motoneurons were also choline acetyltransferase (ChAT)- and acetylcholinesterase (AChE)-positive. On the other hand a large population of ChAT- and AChE-positive motoneurons were devoid of CGRP-immunoreactivity. It is probable that CGRP/ChAT/AChE-positive cells surrounded by SP-positive fibres have different functions in motoric nervous system than the CGRP-negative ChAT/AChE-positive cells, which are surrounded by ENK-immunoreactive fibres. © 1990 Springer-Verlag.

引用

页码：473 / 477

页数：5

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