DETECTION OF ERYTHROMYCIN RESISTANCE BY THE POLYMERASE CHAIN-REACTION USING PRIMERS IN CONSERVED REGIONS OF ERM RIBOSOMAL-RNA METHYLASE GENES

被引：76

作者：

ARTHUR, M ^{[1
]}

MOLINAS, C ^{[1
]}

MABILAT, C ^{[1
]}

COURVALIN, P ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO,CTR MOLEC GENET,LA JOLLA,CA 92093

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1990年 / 34卷 / 10期

关键词：

D O I：

10.1128/AAC.34.10.2024

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Genes belonging to different erm DNA hybridization classes were selectively amplified by polymerase chain reaction with a pair of oligonucleotides that corresponded to amino acid motifs in known ERM methylases. Identification of the resistance mechanism was possible despite substantial nucleotide sequence diversity among the erythromycin resistance genes.

引用

页码：2024 / 2026

页数：3

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