NEW CHIRAL AND ISOMERIC CYCLOPROPYL KETOXIME PROPANOLAMINE DERIVATIVES WITH POTENT BETA-ADRENERGIC BLOCKING PROPERTIES

被引：32

作者：

BOUZOUBAA, M

LECLERC, G

RAKHIT, S

ANDERMANN, G

机构：

[1] INST PHARMACOL,DEPT PHARMACOCHIM,CNRS,ERA 142,INSERM,U206,F-67000 STRASBOURG,FRANCE

[2] LABS POS,F-68240 KAYSERSBERG,FRANCE

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1985年 / 28卷 / 07期

关键词：

D O I：

10.1021/jm00145a008

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：896 / 900

页数：5

共 25 条

[1]

AMLAIKY N, 1981, J ORG CHEM, V47, P517

[2]

ARIENS EJ, 1957, ARCH INT PHARMACOD T, V110, P275

[3] SOME QUANTITATIVE USES OF DRUG ANTAGONISTS [J].

ARUNLAKSHANA, O ;

SCHILD, HO .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1959, 14 (01) :48-58

[4] SYNTHESIS OF(R)-EPICHLOROHYDRIN AND (S)-EPICHLOROHYDRIN [J].

BALDWIN, JJ ;

RAAB, AW ;

MENSLER, K ;

ARISON, BH ;

MCCLURE, DE .

JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (25) :4876-4878

[5] USE OF (S)-(TRIFLOXYMETHYL)OXIRANE IN THE SYNTHESIS OF A CHIRAL BETA-ADRENOCEPTOR ANTAGONIST, (R) AND (S)-9-[[3-(TERT-BUTYLAMINO)-2-HYDROXYPROPYL]OXIMINO]FLUORENE [J].

BALDWIN, JJ ;

MCCLURE, DE ;

GROSS, DM ;

WILLIAMS, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (08) :931-936

[6] STEREOCHEMISTRY OF ADRENERGIC RECEPTORS - NEWER CONCEPTS ON MOLECULAR MECHANISM OF ACTION OF CATECHOLAMINES AND ANTIADRENERGIC DRUGS AT RECEPTOR LEVEL [J].

BELLEAU, B .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1967, 139 (A3) :580-&

[7]

BOUZOUBAA M, 1984, J MED CHEM, V27, P1291, DOI 10.1021/jm00376a011

[8]

BOUZOUBAA M, 1984, TETRAHEDRON LETT, V29, P3067

[9] FLOW NUCLEAR MAGNETIC-RESONANCE STUDY OF DEHYDRATION OF TETRAHEDRAL INTERMEDIATE RESULTING FROM ADDITION OF HYDROXYLAMINE TO ACETALDEHYDE [J].

COCIVERA, M ;

FYFE, CA ;

EFFIO, A ;

VAISH, SP ;

CHEN, HE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (06) :1573-1578

[10] Studies on the relationship between chemical constitution and physiological action. V. Molecular dissymmetry and physiological activity. [J].

Easson, LH ;

Stedman, E .

BIOCHEMICAL JOURNAL, 1933, 27 :1257-1266

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