MYOCLONIC SPASMS DURING TREATMENT WITH HIGH-DOSES OF INTRAVENOUS MORPHINE IN RENAL-FAILURE

被引：46

作者：

SJOGREN, P ^{[1
]}

DRAGSTED, L ^{[1
]}

CHRISTENSEN, CB ^{[1
]}

机构：

[1] UNIV COPENHAGEN,DEPT PHARMACOL,DK-1168 COPENHAGEN,DENMARK

来源：

ACTA ANAESTHESIOLOGICA SCANDINAVICA | 1993年 / 37卷 / 08期

关键词：

MORPHINE; MORPHINE GLUCURONIDES; MYOCLONIC SPASMS; RENAL FAILURE;

D O I：

10.1111/j.1399-6576.1993.tb03809.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Myoclonic spasms occurred in a patient suffering from renal failure after high doses of continuous intravenous morphine (100 mg/h). The concentrations of morphine, morphine-6-glucuronide and morphine-3-glucoronide (mumol/l) in plasma were: 1.93, 52.06 and 381.8, and in cerebrospinal fluid were: 1.02, 5.86 and 61.82, respectively. The role of morphine and morphine glucuronides in myoclonic spasms is discussed.

引用

页码：780 / 782

页数：3

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