CLONING AND SEQUENCE OF THE XENOPUS-LAEVIS HOMOLOG OF THE MIDKINE CDNA

被引：11

作者：

FU, C

MAMINTASMITH, MLD

GUO, C

DEUEL, TF

机构：

[1] JEWISH HOSP ST LOUIS,ST LOUIS,MO 63110

[2] WASHINGTON UNIV,SCH MED,DEPT MED,ST LOUIS,MO 63110

[3] WASHINGTON UNIV,SCH MED,DEPT BIOCHEM & MOLEC BIOPHYS,ST LOUIS,MO 63110

来源：

GENE | 1994年 / 146卷 / 02期

关键词：

SEQUENCE HOMOLOGY; HEPARIN-BINDING FACTOR; PLEIOTROPHIN; EVOLUTIONAL CONSERVATION;

D O I：

10.1016/0378-1119(94)90312-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The Xenopus laevis (X1) homologue of the midkine-encoding gene (MK) has been isolated and sequenced from a X. laevis cDNA library made from the head region of stage-22 embryo. The nucleotide and deduced amino-acid sequences show a high degree of conservation with the avian and mammalian MK and pleiotrophin (PTN) genes and gene products. Highly conserved domains may indicate important regions for the function of the MK and PTN proteins.

引用

页码：311 / 312

页数：2

共 9 条

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