ISOTOPIC AND NUCLEAR ANALYTICAL TECHNIQUES IN BIOLOGICAL-SYSTEMS - A CRITICAL-STUDY .10. ELEMENTAL ISOTOPE-DILUTION ANALYSIS WITH RADIOACTIVE AND STABLE ISOTOPES

被引：14

作者：

FASSETT, JD

机构：

[1] National Institute of Standards and Technology, Technology Administration, Department of Commerce, Gaithersburg

来源：

PURE AND APPLIED CHEMISTRY | 1995年 / 67卷 / 11期

关键词：

D O I：

10.1351/pac199567111943

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Isotope dilution is a method of-chemical analysis based on the mixing (or dilution) of a radioisotope or a separated stable isotope with its natural isotope(s) in the sample. The activity ratio or isotopic ratio of the mixture defines the concentration of the analyte, which is a tremendous advantage for measurement since quantitative separation of the analyte is not required. The technique has a multitude of variations and has been combined with many classical and instrumental procedures used in analytical chemistry. The technique is noted for its accuracy. This review focuses on the application of the technique in the determination of elemental concentrations in biological systems.

引用

页码：1943 / 1949

页数：7

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