ANALYSIS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 LTR-LTR JUNCTIONS IN PERIPHERAL-BLOOD MONONUCLEAR-CELLS OF INFECTED INDIVIDUALS

被引:29
作者
JURRIAANS, S [1 ]
DERONDE, A [1 ]
DEKKER, J [1 ]
GOUDSMIT, J [1 ]
CORNELISSEN, M [1 ]
机构
[1] UNIV UTRECHT,INST VIROL,3584 CL UTRECHT,NETHERLANDS
关键词
D O I
10.1099/0022-1317-73-6-1537
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Circularized DNA species containing two long terminal repeat circle junctions were analysed in peripheral blood mononuclear cells of human immunodeficiency virus type 1 (HIV-1)-infected individuals. The circle junction fragments found could be classified into four groups: fragments containing a normal circle junction, fragments with deletions at the circle junction, fragments containing the primer binding site inserted at the circle junction, and fragments containing insertions at the circle junction derived from other regions of the HIV-1 genome.
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页码:1537 / 1541
页数:5
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