GENERATION OF PYRROLES IN THE REACTION OF LEVUGLANDIN E(2) WITH PROTEINS

被引：47

作者：

IYER, RS ^{[1
]}

KOBIERSKI, ME ^{[1
]}

SALOMON, RG ^{[1
]}

机构：

[1] CASE WESTERN RESERVE UNIV, DEPT CHEM, CLEVELAND, OH 44106 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 20期

关键词：

D O I：

10.1021/jo00099a039

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of levuglandin (LG) E(2) with proteins generates pyrrole derivatives that are detected with an Ehrlich assay. The pyrroles formed by the reaction of LGE(2) with simple amines are chemically sensitive, but a stable derivative is obtained by trifluoroacetylation.

引用

页码：6038 / 6043

页数：6

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