STRESS PROTEINS - THE EXERCISE RESPONSE

被引：95

作者：

LOCKE, M ^{[1
]}

NOBLE, EG ^{[1
]}

机构：

[1] UNIV WESTERN ONTARIO,FAC KINESIOL,LONDON,ON N6A 5B7,CANADA

来源：

CANADIAN JOURNAL OF APPLIED PHYSIOLOGY-REVUE CANADIENNE DE PHYSIOLOGIE APPLIQUEE | 1995年 / 20卷 / 02期

关键词：

EXERCISE; HEAT SHOCK; HSP; 72; SKELETAL MUSCLE;

D O I：

10.1139/h95-011

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

A class of proteins that under-goes preferential synthesis following a variety of stressors has been demonstrated to carry out important cellular-functions under both stressed and nonstressed conditions. These so-called heal shock (HSP) or stress (SP) proteins have been termed ''molecular chaperones'' and play important roles in cellular transportation, assembly/degradation, and cell survival. This review provides a basic introduction to the function and regulation of these proteins. Emphasis is placed on members of the HSP 70 family of proteins (especially HSP 72) and their role in cellular protection, their pattern of distribution in skeletal muscle, and changes in their expression following exercise and exercise training.

引用

页码：155 / 167

页数：13