SUBCELLULAR-LOCALIZATION OF INOSITOL LIPID KINASES IN RAT-LIVER

被引：77

作者：

COCKCROFT, S ^{[1
]}

TAYLOR, JA ^{[1
]}

JUDAH, JD ^{[1
]}

机构：

[1] UNIV LONDON UNIV COLL, SCH MED, DEPT EXPTL PATHOL, LONDON WC1E 6JJ, ENGLAND

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1985年 / 845卷 / 02期

关键词：

D O I：

10.1016/0167-4889(85)90173-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The subcellular distribution of the enzymes which phosphorylate phosphatidylinositol sequentially to form phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate was investigated in rat liver. Whilst phosphatidylinositol kinase is present in golgi, lysosomes and plasma membranes, the kinase that forms phosphatidylinositol 4,5-bisphosphate is localized predominantly at the plasma membrane. The role of the inositol lipid kinases in cell function is discussed.

引用

页码：163 / 170

页数：8

共 33 条

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